Tag Archives: Johnson & Johnson

Top Pharma News and Developments that Made Headlines in July

These are last month’s pharma news and developments brought to you by Congress Bookers, a reliable accommodation partner for lead pharma companies worldwide.

 

Amgen signs collaboration agreement with Array BioPharma

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Amgen and Array BioPharma announced a preclinical license and collaboration agreement in inflammation.

Under the agreement, the two companies will collaborate on the discovery and development of new drugs for autoimmune disorders. Amgen will be responsible for clinical development and commercialization, having exclusive rights to Array’s preclinical program. In turn, upfront and milestone payments will be made by Amgen.

 

Bavarian Nordic partnered with Johnson & Johnson for HIV, HBV shots

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Danish company Bavarian Nordic and Johnson & Johnson have signed a deal worth USD 879M  to develop HIV, HBV shots.

Under the terms of the deal, Bavarian Nordic is granting J&J’s Janssen unit the rights to combine MVA-BN with Janssen’s own AdVac platform in the HIV and HBV programs. In return, Janssen will pay Bavarian Nordic $10 million upfront and up to $836 million in milestones. Bavarian Nordic will design, produce and deliver the MVA needed, while Janssen will handle R&D.

 

Samsung and Merck launched Remicade biosim

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Samsung and Merck & Co. launched Renflexis in the US. Renflexis is 35% cheaper than J&J’s anti-inflammatory med.

Last year, Pfizer launched its version, Inflectra, at a 15% discount. Renflexis is the third biosim to launch in the US after Inflectra and Sandoz’s Zarxio, a biosimilar to Amgen’s Neupogen.

 

Gilead’s Vosevi got US FDA Approval

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The US Food and Drug Administration (FDA) has approved Gilead Sciences’ Vosevi tablets, a single-tablet regimen for the re-treatment of chronic hepatitis C virus (HCV) infection in adults with genotype 1, 2, 3, 4, 5 or 6 previously treated with an NS5A inhibitor-containing regimen, or with genotype 1a or 3 previously treated with a sofosbuvir-containing regimen without an NS5A inhibitor.

The approval is based on data from the Phase 3 POLARIS-1 and POLARIS-4 studies, which evaluated Vosevi during an interval of 12 weeks.

 

Novo Nordisk and Glooko launch co-marketed app

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As a result of Novo Nordisk’s partnership with diabetes health tech startup Glooko a new app was launched. It’s dubbed Cornerstones4Care Powered by Glooko, or the C4C app.

The app allows diabetes patients to measure and track blood glucose, activities and meals. It syncs blood glucose and activity data from a wide array of diabetes or exercise devices.

The app is free for registered C4C online users and can be downloaded from the Apple or Google app stores.

 

AstraZeneca partners with Merck to develop and commercialise cancer drugs

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AstraZeneca and Merck & Co have entered a global oncology collaboration to co-develop and co-commercialise the AstraZeneca’s Lynparza and selumetinib for various cancer types.

Under the agreement, the companies will develop and commercialise Lynparza jointly, as monotherapy and in combination with other potential medicines. Furthermore, they will develop and commercialise Lynparza in combination with their own PD-L1 and PD-1 medicines, Imfinzi and Keytruda.

AstraZeneca and Merck will also co-develop and commercialise selumetinib, the former’s selective inhibitor of MEK, that’s being developed for several indications including thyroid cancer.

The 2 companies will share development and commercialisation costs as well as profits from product sales.

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  • EASL 2018 – 210 rooms in seven 4-star hotels
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  • ECTRIMS 2018 – 620 rooms in ten hotels
  • ESMO 2018 – 1092 rooms in twenty-one 4-star hotels.

 

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January’s Top Pharma News & Developments

These are last month’s pharma news and developments brought to you by Congress Bookers, a reliable accommodation partner for lead pharma companies worldwide.

 

Johnson & Johnson to acquire Actelion for USD 30 billion

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Johnson & Johnson is set to acquire Swiss biotech company Actelion. The deal is valued at USD 30 billion and will give J&J access to Actelion’s research and development pipeline, as well as medicines for rare diseases.

Under the agreement, Actelion will draw out its research and development unit into a standalone company dubbed R&D NewCo, based in Switzerland, and led by Actelion founder and CEO Jean-Paul Clozel.

J&J will initially hold a 16% stake in R&D NewCo, with rights to an additional 16%.

 

Sanofi, MSD ended vaccines JV

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Sanofi Pasteur, the vaccines division of the multinational pharmaceutical company Sanofi, has ended its vaccines joint venture with MSD, a collaboration that spanned more than 20 years.

The move was first announced in March 2016 and the reason was that both companies wanted to pursue their “distinct growth strategies.”

Throughout its existence, Sanofi Pasteur MSD launched several vaccines onto the European market such as Gardasil and Zostavax.

 

Bristol-Myers Squibb entered clinical collaboration with Janssen

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Global biopharmaceutical company Bristol-Myers Squibb has entered a clinical research collaboration with US-based biotechnology company Janssen Biotech.

The aim of the collaboration is to analyse the combination of Bristol-Myers Squibb’s Immuno-Oncology (I-O) agent Opdivo and Janssen’s CD38-directed cytolytic antibody Darzalex in Phase 1b/2 clinical studies in multiple myeloma and solid tumors.

In July 2016, Bristol-Myers Squibb and Janssen signed a clinical research collaboration to evaluate Opdivo and Live Attenuated Double-Deleted (LADD) Listerial monocytogenes cancer immunotherapy in patients with non-small cell lung cancer.

 

Merck teamed up with Palantir for faster drug discovery

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German multinational pharma company Merck has teamed up with US-based data and analysis software company Palantir to enhance drug discovery and development.

In the beginning, the two companies will partner on three of Merck’s business sectors: healthcare, life sciences, and performance materials.

The exact terms of the deal haven’t yet been disclosed.

 

Novo Nordisk partnered Glooko to develop digital health solutions for patients with diabetes

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Health platform for diabetes management Glooko has teamed up with Danish multinational pharmaceutical company Novo Nordisk to develop and brand digital health solutions for people with diabetes.

Under the agreement, the companies are set to deliver personalised, digital services to support people with diabetes in what concerns treatment adherence and blood glucose management. The partnership will also make it easier for healthcare professionals to manage patients by leveraging data reporting.

Novo Nordisk’s Digital Health Platform was developed with IBM Watson Health and it aims to improve treatment outcomes.

 

Novartis in USD 1.6 bln deal with Ionis Pharmaceuticals

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Novartis has entered an agreement with US-based biopharmaceutical company Ionis Pharmaceuticals.

Under the deal, Novartis will pay up to USD 1.6 billion to Ionis and its unit Akcea Therapeutics for the rights to two cardiovascular drugs that aim to lower the level of cholesterol-carrying proteins in the blood, thus reducing the risk of cardiovascular diseases. Furthermore, Novartis will invest USD 50 million in either Ionis or Akcea within the first 18 months, as well as payments worth up to USD 1.4 billion if the drugs turn out  successful.

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Congress Bookers provides a whole range of services needed to organize a group for a medical congress. On our website, you will find a full list of hotel allotments for the most important medical congresses in 2017, regardless of their location. The biggest congresses next year are:

From 60 Pharma companies to 10 Big Pharma companies in 20 Years

We’ve all heard about Novartis, Pfizer, Sanofi and Roche. They’re some of the big guys in the pharma landscape, enjoying increased popularity, splitting the high budgets and revolutionizing the healthcare and pharma industry but what’s the road they took to get here? In order to answer that question, we’re going to analyze the 10 biggest pharma companies nowadays which used to be around 60 distinct companies 20 years ago. Here’s what they did to stand the test of time and grow.

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Novartis

It all dates back to 1970 when Ciba-Geigy was formed by the merger of J. R. Geigy Ltd and CIBA. In 1996, from the merger of Ciba-Geigy and Sandoz Laboratories, Novartis was born. In 2005, Novartis acquired Hexal and Eon Labs, thus growing its generic division Sandoz. A year later, in 2006, Novartis acquired full control of Chiron Corp. for USD 5.1 billion. In 2010, Novartis acquired the world’s largest eye-care company Alcon for USD 39.3 billion. Three years later, in 2012, the company bought Fougera Pharmaceuticals for USD 1.5 billion. In 2016, Novartis acquired Selexys Pharmaceuticals Corporation and SelG1 antibody for reduction of pain crises in sickle cell disease (SCD).

AstraZeneca (AZ)

AstraZeneca  was created in 1999 following the merger of Astra and Zeneca Group. In 2004, AZ completed its first big acquisition of Cambridge Antibody Technology. Later on, in 2007, it acquired MedImmune for about USD 15.2 billion. In 2012, AstraZeneca acquired Ardea Biosciences for USD 1.3 billion. One year later, it acquired Amylin from BMS for USD 4.3 billion and in 2015 acquired ZS Pharma for USD 2.7 billion. In 2015, AstraZeneca bought 55% majority stake in Acerta for USD 4 billion.

Pfizer

In 2000, Pfizer acquired American pharmaceutical company Warner–Lambert for USD 111.8 billion to bring its drug, Lipitor, to market. In 2002, Pfizer aimed to acquire full rights to Pharmacia’s product Celebrex and thus agreed to buy Pharmacia for stock valued at USD 60.0 billion. In 2009, Pfizer bought pharmaceutical company Wyeth for USD 68.0 billion. In 2015, Pfizer acquired Hospira for USD 15.2 billion and announced the merger with Allergan. The latter is considered to be one of the biggest mergers in pharma history. In 2016, Pfizer announced the successful completion of its acquisition of Medivation.

Sanofi

Sanofi resulted from the merger between Sanofi-Synthélabo and Aventis in 2004. The former was created in 1999 when Sanofi merged with Synthélabo. Aventis was formed in 1999 following the merger of Rhône-Poulenc S.A. with Hoechst Marion Roussel (HMR). The latter itself was formed in 1995 from the merger of Hoechst AG with Cassella, Roussel Uclaf and Marion Merrell Dow.

In 2011, Sanofi-Aventis acquired Genzyme and changed its name to Sanofi.

Johnson & Johnson

J&J was founded in 1886 as a medical devices, pharmaceutical and consumer packaged goods company. The pharmaceutical division is made up of Janssen & Cilag. In 2006, Janssen acquired the consumer healthcare business of Pfizer for USD 16.6 billion in what is considered to be the company’s largest M&A deals. In 2013, the company acquired Aragon Pharma and in 2014 it bought Alios BioPharma, Inc. for USD 1.75 billion.

Merck & Co.

Merck was founded in 1668 and is the world’s oldest operating chemical and pharmaceutical company. Merck & Co. was established as a subsidiary of Merck in 1891, but became an independent company in 1917. It is known as MSD (Merck Sharp and Dohme) outside of North America. In 1993, Merck purchased Medco Containment Services Inc. for USD 6 billion. In 2009, Merck merged with Schering-Plough. The latter had acquired Organon from Akzo Nobel in 2007 while Organon resulted from a merger between Diosynth and Organon in 2004. Ten years later, Merck bought Cubist Pharmaceuticals for USD 8.4 billion.

Roche

Roche’s first acquisition took place in 1994 when the company bought Syntex Corporation for USD 5.3 billion. In 2002, Roche’s Japanese subsidiary Nippon Roche merged with Chugai. Following the deal, Roche got a majority stake in the Japanese company. In 2008, Roche acquired Ventana Medical Systems for USD 3.4 billion and in 2009, the company bought Genentech for USD 46.8 billion.

Teva

Teva resulted from the merger between Assia, Zori and Teva in 1976. In 2006, Teva completed its first big acquisition of IVAX Corporation for USD 7.4 billion. In 2011, it acquired Cephalon for USD 6.8 billion. After acquiring Auspex Pharma for USD 3.5 billion in 2015, Teva completed its acquisition of Allergan’s generics business (“Actavis Generics”) in 2016.

Gilead Sciences

Gilead Sciences was founded in June 1987. Over the past 16 years, the company has made several acquisitions. The biggest ones include: CV Therapeutics for USD 1.4 billion in 2009 and USD 10.4 billion acquisition of Pharmasset in 2011.

GlaxoSmithKline (GSK)

GSK was founded in 2000 following the merger of Glaxo Wellcome and SmithKline Beecham. In 2001, GSK acquired Block Drug for USD 1.2 billion. In 2009, GSK acquired Stiefel Laboratories for USD 3.6 bn. 4 years later, in 2013, GSK acquired Human Genome Sciences (HGS) for USD 3 billion. In 2015, GSK completed the acquisition of vaccine business of Novartis and sale of its oncology business to the Swiss drug major in a global deal. Under the agreement, GSK Pharma expanded its vaccine portfolio and took over 120 employees from Novartis to boost its sales in India.

There’s so much pharma history behind all of the big names out there and the evolution is far from reaching an end. We’re looking forward to seeing what these pharma giants have in store during the next couple of years and who’s going to lead the way in the M&A sector.

Congress Bookers provides a whole range of services needed to organize a group for a medical congress. On our website, you will find a full list of hotel allotments for the most important medical congresses in 2017, regardless of their location. The biggest congresses next year are:

Line Up to deliver Johnson & Johnson conference

London-based agency to design all content and branding for September’s MENAP Annual Meeting in Dubai

Heath care giant Johnson & Johnson has appointed Line Up to deliver a regional annual conference in Dubai in September.

The Johnson & Johnson MENAP (Middle East, North Africa and Pakistan) Annual Meeting 2014 will be hosted at The Oberoi Hotel in Dubai’s Business Bay on 14-17 September, where 230 delegates will mark the year’s successes and discuss strategies for future growth.

London-based agency Line Up is responsible for designing all content and branding for the four-day event, which will include a series of plenary talks, break-out sessions and a gala dinner.

It is also shooting and editing a series of videos, handling delegate acquisition, having designed a bespoke event website, and will oversee on-site delegate management, organising all entertainment plus the gala dinner.

Associate director Kath Wallace said: “This is a significant international event for Johnson & Johnson, designed to engage employees, regional distributors and local partners across Pakistan, Dubai, Saudi Arabia, Egypt and Morocco. We look forward to helping the firm create a truly memorable event.”

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